Up to the third century, educated people wrote Greek. That includes scripture. It also seems that Carthage was the center of the church, like we would consider Rome. Up to the third/fourth century it would not have been Rome. The Caesars in Rome outlawed Christianity. Even the famous, Hippolytus, who lived in Rome, wrote in Greek.
As the peoples across the Mediterranean--Rome, and the Roman empire, became more knowledgeable of Christianity, they wanted the texts in their own language--Latin. More and more "Bibles" in Latin were written, read, and spread. There wasn't one, official, book. Only with Jerome, 400 AD, was a common, Latin text of Scripture published, known as the Vulgate. Latin was the common language--or the vulgar language. There was a lot of written works for the 70 people, who were compiling the Bible, to choose. There were writings from the Apostolic Fathers, such as Barnabas, the Didache, letters from popes and other leaders.
One of the 70 compilers of our Bible was Epenetus. He was a companion of Paul in Asia-Minor Romans 16: 5. His center of comfort, however, was Carthage. He is known as Epenetus of Carthage and is considered a saint.
From Greek Orthodox Church of America.






